HORDB

ID: hor002862
Uniprot ID: Q00676
Protein name: Bradykinin-like neuropeptide
Gene name: LUQ-1
Organism: Aplysia californica (California sea hare)
Family: NA
Source: animal
Expression: Neuron L5.
Disease: NA
Comments: NA
Taxonomy: Aplysia (genus), Aplysiidae (family), Aplysioidea (superfamily), Aplysiida (order), Tectipleura, Euthyneura, Heterobranchia (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: MKRSRGPSPRR
Length: 11(81-91)
Propeptide: MTSSIYGFITLSVVALISQTTCRSLDLLLDGDFNNGLASFDGSSKWSRLPLEFLAAFDLDPHQAQGQHLAEAPEAPLMEAMKRSRGPSPRRLRSYLRRAAGLRGMKRKMFWQPLGYMPASARAHNNVPEVVNENSQDSGTNVFRYG
Signal peptide: MTSSIYGFITLSVVALISQTTCRS
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Function: May have important functions in renal physiology and in animal behavior, as does bradykinin.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002862_AF2.pdb

hor002862_ESM.pdb

Mass:	150609	Formula:	C53H98N24O14S
Absent amino acids:	ACDEFHILNQTVWY	Common amino acids:	R
pI:	12.98	Basic residues:	5
Polar residues:	3	Hydrophobic residues:	0
Hydrophobicity:	-229.09	Boman Index:	-6874
Half-Life:	30 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	0
Instability Index:	19113.64	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 2029336
Title: A bradykinin-like neuropeptide precursor gene is expressed in neuron L5 of Aplysia californica.